* The Keys quadruplets (born on June 4,1915 in Hollis, Oklahoma), were the first same sex quadruplets known to survive to adulthood.
* The Dionne quintuplets (born on May 28, 1934 near Corbeil, Ontario, Canada) were the first quintuplets known to survive their infancy.
* The Rosenkowitz sextuplets (born on January 11, 1974 in Cape Town, South Africa) were the first sextuplets known to survive their infancy.
* The Walton sextuplets (born on November 11, 1983 in Liverpool) were the first sextuplets born in the United Kingdom known to survive their infancy.
* The Frustaci septuplets (born on May 21, 1985) were the first septuplets to be born in the United States. Only three babies survived.
* The Dilley sextuplets (born on May 25, 1993 in Indianapolis) were the first surviving sextuplets to be born in the United States.
* The McCaughey septuplets (born on November 19, 1997 in Des Moines, Iowa) were the world's first surviving set of septuplets.
* The Humair septuplets (born on January 14, 1998 in Abha, Saudi Arabia) were the world's second surviving set of septuplets, born to a 40-year-old mother.
* The Chukwu octuplets (born in December 1998 in Houston) were the first set of octuplets born in the United States. The smallest of the octuplets, Odera, died a week after birth.
* The Qahtani septuplets (born on July 12, 2001 in Washington, DC) were the third set of septuplets to live past infancy.
* The Dahm Sisters were the only Playboy triplet centerfolds.
* The Armstrong triplets - Lil, Helen and Kate, were the first triplets to all be accepted to Cambridge University.[2]
* The Creel Triplets - Leanna, Monica, and Joy born August 27, 1970 starred in Parent Trap 3, and Parent Trap 4: Hawaiian Honeymoon, two Disney made-for-TV movies.
* The Brino quadruplets were born on September 21, 1998 in Woodland Hills, California to Tony and Shawna Brino, and have all appeared in the popular television series 7th Heaven when they were infants as the twin boys born in season 3- when they all started to look different the only girl (Miranda) stopped appearing in the show, and Zachary and Lorenzo starred in the first episode they were credited in. From then on, only Nikolas and Lorenzo Brino starred in the show, and did through the show's last season, season 10.
* The Haden Triplets born in New York City on October 11, 1971 were Petra, Tanya and Rachel.
